The printed circuit board(PCB) technology is applied to circuit design generally. If it is combined with thick-film process,the circuit layout design,in which the complicated connection and many devices are mounted in its limited room, can be implemented. The outstanding advantages of the thick- film hybrid circuit were demonstrated by theoretical analysis of three defferent design schemes of circuit layout design. It is the unique one which can meet the requirement of the circuit design scheme. According to the boundary dimension requirement of the circuit,the circuit performance and device encapsulation mode were considered thoroughly,and the rationality and realizability of the design scheme were validated by reasonable circuit segmenting design and layout design. The outstanding superiority of thick-film process was reflected in the circuit layout design. The difficulty that the conventional methods for circuit layout design could not overcome was solved easily.