Obesity, not only defined as excessive fat accumulation, but also implies abnormal fat distribution. The increasing visceral adipose tissue is a risk factor for multiple metabolic diseases, such as Type 2 diabetes and cardiovascular disease. Adipose tissue regulates the sensitivity of insulin and insulin signal pathway by secretion of various adipokines and inflammatory factors. Therefore, study of adipose tissue distribution and the characteristics of endocrine is of great significant in prevention and treatment of obesity and related diseases.