Objective To assess the clinical benefici al of early thrombolysis therapy in pre-hospital on the patients with inferior m yocardial infarction and its effection for survival rate.Methods The study group consisted of 100 cases who call the emergency number-120 and utilize thrombolysis therapy in pre-hospital. The cont rol group consisted of 80 cases without giving thrombolysis therapy. The patient s were divided into three groups: A (30 cases), B (34 cases), C (36 cases) by th e time from fall ill to treatment. The difference was observed among coronary ar tery reperfusion rate, heart function, arrhythmia, low blood press state,in-hos pital mortality after thrombolysis therapy.Results There is significant difference on reperfusion rate and mortality between the three subgroups (P0.05).There is significant difference on reperfusion rate and mortality between thrombolysis and control gr oup too (P0.05).Conclusion (1)The earlier the throm bolysis therapy is used on the patients with inferior myocardial infarction, the higher the coronary artery reperfusion rate and survival rate are. (2) The acut e inferior myocardial infarction patients without controlled indication suitable thrombolysis therapy in pre-hospital.