Copper-cerium layer double hydroxide as a novel tool for melatonin detection in sleep therapy tablets

an oxygen bridge. Owing to these properties, the proposed sensor exhibited excellent electrocatalytic behaviour, demonstrating a wide linear detection range (30 nM to 1200 µM), with a limit of detection and limit of quantification of 6.8 nM and 22.6 nM, respectively, in real sample Nizleep Pills compared with other sleep therapy tablets. The sensor demonstrated high selectivity (RSD = 2.83%). Moreover, it retained 74% of its initial response after 100 continuous cycles, indicating good stability. The Cu-Ce LDH electrocatalyst demonstrated excellent electron transfer, good stability and reproducibility. Furthermore, the reproducibility (RSD = 1.28%) for six modified electrodes highlighted its potential as a sensitive and reliable tool for pharmaceutical applications.