Clinical and Biological Effects of Long-Term Lithium Treatment in Older Adults With Amnestic Mild Cognitive Impairment: A Randomized Clinical Trial

In elderly patients with minimal cognitive impairment, the addition of low-dose lithium (blood levels 0.25 mEq/L to 0.5 mEq/L) was associated with lower loss of cognitive function. Risks were minimal. This idea has reached the popular press.