Summary Changes in biochemical and microbiological quality of silverside during two drying process were investigated. Total fatty acid and amino acid contents in silverside were 5.42 and 10.9 g 100 g −1 fresh sample, respectively, in which, palmitic acid and glutamic acid were the most abundant. N‐3 and n‐6 polyunsaturated fatty acids (PUFA) levels were 0.59 and 0.62 g 100 g −1 fresh silverside respectively. After hot air and solar drying treatments, Peroxide value and thiobarbituric acid reactive substances of the total lipids increased significantly ( P < 0.05) to reach 2.58 and 3.41 meq active O 2 kg −1 oil and 0.87 and 1.27 mg MA kg −1 oil, respectively. Fatty acid profile of non‐polar lipid remains unchanged during experimental drying process. However, PUFA (% of total fatty acids) of polar lipid decreased significantly ( P < 0.05) during both drying process with lower levels in solar drying process. Drying conditions had a significant effect on the microbiological quality. Therefore, mesophiles and total coliforms increased within drying treatment with higher counts in solar drying process.