Thyroid Cancer Screening in South Korea Increases Detection of Papillary Cancers with No Impact on Other Subtypes or Thyroid Cancer Mortality

甲状腺癌 医学 入射(几何) 甲状腺乳突癌 癌症 癌症登记处 内科学 甲状腺 肿瘤科 甲状腺疾病 光学 物理
作者
Hyeong Sik Ahn,Hyun Jung Kim,Kyoung Hoon Kim,Young Sung Lee,Seung Jin Han,Yuri Kim,Min Ji Ko,Juan P. Brito
出处
期刊:Thyroid [Mary Ann Liebert, Inc.]
卷期号:26 (11): 1535-1540 被引量:185
标识
DOI:10.1089/thy.2016.0075
摘要

Background: The incidence of thyroid cancer has increased worldwide. The country where the incidence has increased most is South Korea. The goal of this study is to understand the magnitude of association between opportunistic thyroid cancer screening and thyroid cancer incidence, thyroid cancer subtype, and disease-specific mortality. Methods: We used the 2010 Korea Community Health Survey, which queried 226,873 individuals if they had been screened for thyroid cancer in the last two years. Thyroid cancer incidence data from 2008 to 2010 were obtained from the Korea Cancer registry data, and mortality data from 2007–2010 were obtained from the Statistics Korea database. The ecological association between thyroid screening and thyroid cancer incidence and mortality by age and sex were examined across Korea's 16 administrative regions by general linear regression models. Results: Between 2008 and 2010, the incidence of thyroid cancer was 64.1 per 100,000 individuals: the incidence in females was 107.3 and in males was 21.1. There was a strong positive correlation between regional thyroid cancer screening and regional thyroid cancer incidence (r = 0.77, [95% confidence interval 0.70–0.82]). The magnitude of correlation was higher for females (r = 0.88 [CI 0.83–0.92]) than in males (r = 0.76 [CI 0.67–0.84]) in any age group. Thyroid screening was only associated with increased detection of papillary thyroid cancer (r = 0.74 [CI 0.59–0.88]); and not associated with mortality (r = −0.08 [CI −0.59–0.63]) due to thyroid cancer. Conclusions: The magnitude of association between thyroid cancer screening in South Korea and the incidence of thyroid cancer strongly suggests that screening is the most important driver of the epidemic of thyroid cancer, particularly among females. Thyroid cancer screening, however, was only associated with the increase of one tumor histology, papillary thyroid cancer, and it did not have any association with thyroid cancer mortality. The extent to which opportunistic thyroid cancer screening is converting thousands of asymptomatic persons to cancer patients without any known benefit to them needs to be examined carefully.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
3秒前
科研通AI5应助zxy采纳,获得10
3秒前
现代夏青完成签到 ,获得积分10
4秒前
大yo知闲闲完成签到 ,获得积分10
4秒前
kk发布了新的文献求助10
9秒前
糯米糍发布了新的文献求助20
9秒前
白茶完成签到 ,获得积分10
11秒前
Kun发布了新的文献求助10
12秒前
打打应助发论文采纳,获得10
12秒前
12秒前
pluto应助司空三毒采纳,获得10
12秒前
16秒前
英俊的铭应助23xyke采纳,获得10
17秒前
小橙完成签到,获得积分10
19秒前
小凯同学完成签到 ,获得积分10
21秒前
kk发布了新的文献求助10
21秒前
苗玉完成签到,获得积分10
25秒前
25秒前
pluto应助张长剑采纳,获得10
27秒前
28秒前
你以为你是谁应助dap采纳,获得10
28秒前
29秒前
大木发布了新的文献求助10
33秒前
33秒前
33秒前
35秒前
情怀应助maodou采纳,获得10
37秒前
23xyke发布了新的文献求助10
39秒前
大木完成签到,获得积分20
40秒前
40秒前
evny完成签到,获得积分10
41秒前
42秒前
游美女发布了新的文献求助20
42秒前
42秒前
科研dog完成签到,获得积分10
43秒前
43秒前
ray发布了新的文献求助30
45秒前
Jasper应助ll采纳,获得10
46秒前
科研通AI2S应助Steven采纳,获得10
46秒前
深情安青应助时尚凝海采纳,获得30
46秒前
高分求助中
【此为提示信息,请勿应助】请按要求发布求助,避免被关 20000
Continuum Thermodynamics and Material Modelling 2000
Encyclopedia of Geology (2nd Edition) 2000
105th Edition CRC Handbook of Chemistry and Physics 1600
Maneuvering of a Damaged Navy Combatant 650
Периодизация спортивной тренировки. Общая теория и её практическое применение 310
Mixing the elements of mass customisation 300
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 物理 生物化学 纳米技术 计算机科学 化学工程 内科学 复合材料 物理化学 电极 遗传学 量子力学 基因 冶金 催化作用
热门帖子
关注 科研通微信公众号,转发送积分 3778901
求助须知:如何正确求助?哪些是违规求助? 3324431
关于积分的说明 10218443
捐赠科研通 3039495
什么是DOI,文献DOI怎么找? 1668204
邀请新用户注册赠送积分活动 798591
科研通“疑难数据库(出版商)”最低求助积分说明 758440