Частота встречаемости редких форм иммунохимических вариантов иммуноглобулинов у больных с множественной миеломой и влияние их на выживаемость

The article presents the results of studies of rare forms of immunoglobulins, their frequency of occurrence of the most common and rare forms of immunochemical variant Ig Amyeloma, Ig E,IgA-myeloma, Ig D-myeloma patients with multiple myeloma residents of Kirghizia, which have a significant impact on patient survival. These studies are being conducted for the first time in the comparative analysis in the frequency of immunochemical version of kirghiz population and the Russian-speaking population of Kirghizia. According to the results of our study on assessing the impact of immunoglobulin class on outcome of multiple myeloma, the survival rate of patients with Ig Amyeloma, Ig D-myeloma and myeloma IgE, IgA is much lower compared with patients suffering from Ig G-myeloma. MM patients kirghiz nationality recorded in the form of immunochemical embodiment 65 % Ig A–myeloma cases, Ig D-myeloma in 1,5 % cases, IgE myeloma 0,5 % cases, and when detected early uptake of primary chronic kidney disease and myeloma Ig G-recorded in 33 % cases. Based on test results of clinical and laboratory parameters and chronic renal failure in IgA, Ig D, Ig E-myeloma compared with IgG-myeloma for more malignant disease. This requires a timely selection of therapy and chemotherapy program selection.