悬雍垂腭咽成形术
医学
呼吸不足
软腭
阻塞性睡眠呼吸暂停
外科
统计显著性
咽
入射(几何)
耳鼻咽喉科
麻醉
呼吸暂停
多导睡眠图
内科学
光学
物理
作者
Chunhui Chen,X. Y. Zhang,Ren-Yuan Zhu,Hong-yan Zou,Bing Li,Liang Li,Zhihong Lin,Zhengwei Yu,Wei Chen
标识
DOI:10.3760/cma.j.cn115330-20210707-00436
摘要
Objective: To explore the efficacy of relocation and expansion pharyngoplasty by suspension sutures in the treatment of obstructive sleep apnea hypopnea syndrome (OSAHS). Methods: Seventy-three patients(including 60 males and 13 females) with OSAHS admitted to the department of otorhinolaryngology of our hospital in recent two years were retrospectively analyzed. All the patients had velopharyngeal obstructionevaluated by electronic endoscopic Müller test and were divided into control group (34 cases) and observation group (39 cases). The patients in the control group were performed modified uvulopalatopharyngoplasty, while those in the observation group were performed relocation and expansion pharyngoplasty by suspension sutures.The scores of ESS, AHI and LSaO2 before and after treatment were collected and compared. Results: The total effective rate of the observation group was 94.87%, which was significantly higher than 79.41% of the control group. The AHI was lower and LSaO2 value was higher (χ2=-1. 896,-1. 968,P<0.05)in the observation group. The sleeping symptoms and quality of life of the two groups were significantly improved. The ESS score of the observation group was decreased more significantly than that of the control group after treatment, and the difference was statistically significant (χ2=-1.451,P<0.05). The incidence of foreign body sensation in pharynx of the observation group (89.74%) was higher than that of the control group (55.88%), and the postoperative bleeding and postoperative recurrence rate (0.00%, 2.56%) was lower than that of the control group (8.82%, 14.70%)with statistical significance (χ2=4.738,4.249,4.119,P<0.05).The incidence of transient nasopharyngeal reflux in both groups was low and statistically insignificant (χ2=0.629,P>0.05). Conclusions: Preoperative strict screening of indications plays an important role in the selection of palatopharyngeal surgery methods and curative effect. Relocation and expansion pharyngoplasty by suspension sutures can improve the clinical efficacy of OSAHS with better safety and less recurrence.目的: 探讨采用移位-线牵拉扩张咽成形术治疗软腭口咽平面阻塞为主的阻塞性睡眠呼吸暂停低通气综合征(OSAHS)的临床疗效。 方法: 回顾性分析2017年10月至2019年10月广东省中医院耳鼻咽喉头颈科收治的经确诊为OSAHS患者73例临床资料,男60例,女13例,年龄29~59(44.02±4.18)岁,均进行电子内镜的Müller试验检查提示为软腭口咽平面阻塞为主,按入院手术时间前后分为对照组34例和观察组39例:对照组采用改良悬雍垂腭咽成形术,观察组采用联合移位-线牵拉扩张咽成形术进行治疗。收集对比两组患者治疗前后的嗜睡量表(Epworth Sleepiness Scale,ESS)评分、呼吸暂停低通气指数(AHI)、最低动脉血压饱和度(LSaO2)及术后出血率、术后鼻咽反流、术后咽异物感、手术1年后复发率。依据2009年中华医学会耳鼻咽喉头颈外科学分会《阻塞性睡眠呼吸暂停低通气综合征诊断和外科治疗指南》结合临床实际运用对疗效的判定(分为治愈、显效、有效及无效),总有效例数为治愈、显效及有效患者例数的总和。采用SPSS 22.0软件进行统计学分析。 结果: 观察组的总有效率为94.87%,显著高于对照组的79.41%(AHI更低,LSaO2值更高,χ2分别为-1.896、-1.968,P<0.05);两组患者嗜睡症状及生活质量明显好转,观察组治疗后比对照组的ESS评分下降更明显,差异有统计学意义(χ2=-1.451,P<0.05);观察组的咽异物感发生率(89.74%)比对照组(55.88%)高、术后出血的发生率及术后复发率(0,2.56%)较对照组(8.82%,14.70%)更低,差异均有统计学意义(χ2分别为4.738、4.249、4.119,P<0.05);两组的短暂鼻咽反流发生率均较低,差异无统计学意义(χ2=0.629,P>0.05)。 结论: 术前严格筛选适应症和手术方法对腭咽部手术疗效发挥重要作用。与改良悬雍垂腭咽成形术相比,联合移位-线牵拉扩张咽成形术能更有效提高腭咽平面阻塞 为主的OSAHS的临床疗效,安全性较好。.
科研通智能强力驱动
Strongly Powered by AbleSci AI