胶束
材料科学
MTT法
核化学
粒径
活力测定
吸附
多孔性
打赌理论
化学工程
形态学(生物学)
微观结构
纳米技术
化学
有机化学
细胞生长
冶金
体外
水溶液
复合材料
生物化学
生物
工程类
遗传学
作者
Reza Akhavan‐Sigari,Malihe Zeraati,Mohammadreza Moghaddam‐Manesh,Parya Kazemzadeh,Sara Hosseinzadegan,Narendra Pal Singh Chauhan,Ghasem Sargazi
出处
期刊:BMC chemistry
[Springer Nature]
日期:2022-03-05
卷期号:16 (1)
被引量:12
标识
DOI:10.1186/s13065-022-00804-2
摘要
The ultrasonic assisted reverse micelle method (UARM) was used to synthesize Cu-MOF from Cu(NO3)2·3H2O and 2,6-pyridine dicarboxylic acid in a 1:1 molar proportion. It has been characterized using FT-IR, XRD, nitrogen adsorption analysis, SEM and TEM-EDX. The morphology of Cu-MOFs was spherical, with an average particle size distribution of less than 100 nm. Using BET analysis, the surface area of Cu-MOF was found to be 284.94 m2/g. The porous morphology of Cu-MOF was also suggested by SEM and TEM analyses. It has anticancer properties against MCF-7 breast cancer cells. Cytotoxicity testing was performed on MCF-7 breast cancer cells using the MTT cell viability assay, and cell proliferation and viability were found to be approximately 24% higher than the control.
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