Advancements in calcific aortic valve disease

Currently, there is no successful drug treatment to prevent or reverse the occurrence and progress of calcifying aortic valve disease. In recent years, microRNAs (miRNAs) have been found to play important roles in many inflammatory diseases. Mechanism of CircANKRD36 regulating cell heterogeneity and endothelial mesenchymal transition in aortic valve stromal cells by regulating miR-599 and TGF-β signaling pathwayInternational Journal of CardiologyVol. 352PreviewTo explore the mechanism of CircANKRD36 regulating cell heterogeneity and endothelial mesenchymal transition in aortic valve stromal cells by regulating miR-599 and TGF-β signaling pathway. Full-Text PDF