医学
心肌梗塞
再灌注损伤
缺血
心脏病学
心肌缺血
HMGB1
再灌注治疗
内科学
炎症
作者
Jichun Wang,Xiaorong Hu,Hong Jiang
标识
DOI:10.1016/j.ijcard.2013.12.273
摘要
Myocardial reperfusion therapy is the optimal therapeutic strategy for acute myocardial infarction to preserve myocardial viability and function by reversing myocardial ischemia and reducing the infarct size [1]. However, the subsequent ischemia and reperfusion (I/R) injury may attenuate the therapeutic benefit [1]. Although reperfusion therapy is essential for the survival of ischemic tissue, reperfusion itself may cause additional cellular injury by causing local myocardial inflammation, accompanying with apoptosis, which could result in myocardial cell damage [2].
科研通智能强力驱动
Strongly Powered by AbleSci AI