化学
活性氧
过剩1
烟酰胺腺嘌呤二核苷酸磷酸
葡萄糖摄取
NADPH氧化酶
生物化学
分子生物学
氧化酶试验
内分泌学
生物
酶
胰岛素
作者
Su Jin Lee,Cung Hoa Thien Quach,Kyung‐Ho Jung,Jin-Young Paik,Jin Hee Lee,Jin Won Park,Kyung-Han Lee
出处
期刊:Journal of nuclear medicine
[Society of Nuclear Medicine]
日期:2014-09-11
卷期号:55 (10): 1699-1705
被引量:74
标识
DOI:10.2967/jnumed.114.139428
摘要
oxLDL is a strong stimulator of macrophage (18)F-FDG uptake and glycolysis through upregulation of GLUT1 and hexokinase. This metabolic response is mediated by Nox2-dependent ROS generation that promotes HIF-1α activation.
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