Abnormal neurotransmitter activation in patients with chronic insomnia

Objective:To investigate neurotransmitter activation in patients with chronic insomnia.Methods:Encephalofluctuogram(EFG)were obtained from 51 patients with chronic insomnia and 51 healthy individuals, Parameters of EFG that reflect neurotransmitter activation were analysed.Results:S1 and S2 of neurotransmitter list in EFG are obviously lowered in patients with chronic insomnia compared with healthy individuals.Conclusions:Neurotransmitter GABA(S1) and Glu(S2) may be involved in the patients with chronic insomnia.