Radiofrequency Ablation and Transcatheter Arterial Chemoembolization in Primary Hepatic Carcinoma

Objective To investigate the clinical effect of a combination therapy of percutaneous radiofrequency ablation(RFA)and transcatheter arterial chemoembolization(TACE) in primary hepatic carcinoma.Methods Among 106 patients with hepatic carcinoma,32 patients received a combination therapy of TACE and RFA(combination group),38 patients TACE alone,and the rest 36 patients RFA alone.Moreover,there was no significant difference in mean age,tumor size and liver function grade among the three groups.Results The complete necrosis rate of tumor accounted for 93.7% in combination group,which was significantly higher than that of TACE group and RFA group(50.0% and 44.4%,respectively,P0.05).The local recurrence rate of tumor in the combmation group,TACE group and RFA group was 25.0%,31.5%,and 30.5%,respectively,there was no significant difference among the three groups(P0.05).Mean survival duration of combination group was 30.0 months,which was higher than that of TACE group(26.8 months),and? that of RFA group(17.6 months),but there was no significant difference among the three groups(all P0.05).Conclusion percutaneous radiofrequency ablation(RFA)and transcatheter arterial chemoembolization(TACE) in primary hepatic carcinoma could improve tumor complete necrosis rate and extend the patients' survival duration.