Pediocin is often described as small,heat-stable and unmodified peptides.This antimicrobial peptide is a broad-spectrum lactic acid bacteria bacteriocin that shows a particularly strong activity against Listeria monocytogenes.This article summarized the research progress of pediocin's application in food preservation in recent years,analyzed the propect of padiocin as natural food preservative,and further discussed the problems of industrialization development and market application of padiocin.