There are four existing systems of innovation approaches. namely,firm's innovation system approach,national innovation system approach,regional innovation system approach,and sectoral innovation system approach.Now,the literatures pay the new attentions to the innovation system on the industrial cluster and global economy,which are cluster innovation system and global innovation system.This paper tries to build the multi-level architecture on innovation systems' research based upon the literature review. There are two issues that stand out as problematic.One is what is the appropriate architecture to explore the relationships of these evolved innovation systems.and another is what is the correlation when these innovation systems are evolving.Also, the further research suggestions are put forward.