Adverse drug reactions of statins

Statin drug is a category of lipid-lowering agent widely used in clinic and plays an important role in the treatment of various cardiovascular diseases.With the increasing use of these drugs,the adverse drug reactions(ADRs) were reported increasingly.Its common ADRs include statin related-myopathy,hepatic injury,allergic reactions,ophthalmoplegia externa,sexual dysfunction,polyuria,digestive reaction,arthralgia,restless legs syndrome,et al.Recent reports of ADRs of statins and the prevention and cure measures are reviewed in this paper.Clinician and pharmacists should pay more attention to ADRs induced by statins in clinical practice and promote their rational use.