The differences between Mixian honeysuckle and Fengqiu honeysuckle and the differences among different parts of Fengqiu honeysuckle were analyzed by high performance liquid chromatography.The results indicated that chlorogenic acid content:Fengqiu red honeysuckle 3.10%(contrast)Fengqiu honeysuckle 0.095%(p0.05)Mixian honeysuckle 2.22%(p0.01);luteoloside content:Fengqiu red honeysuckle 0.181%(contrast)Fengqiu honeysuckle 0.095%(p0.05)Mixian honeysuckle 0.075%(p0.05);chlorogenic acid content in different parts of Fengqiu honeysuckle:flower bud 2.87%(contrast)leaf 0.84%(p0.01)bud 0.67%(p0.01)branch 0.61%(p0.01),Luteoloside content:bud 0.488%(contrast)leaf 0.397%(p0.01)flower bud 0.095%(p0.01)branch 0.066%(p0.01);chlorogenic acid content in different parts of Fengqiu rad honeysuckle:flower bud 3.10%(contrast)leaf 1.34%(p0.01)bud 1.29%(p0.01)branch 0.92%(p0.01),Luteoloside content:bud 0.329%(contrast)leaf 0.299%(p0.01)flower bud 0.181%(p0.01)branch 0.063%(p0.01).The contents of components of honeysuckle Yu were higher than the minimun standards of China Pharmacopeia(2010ed) and the quality of Fengqiu honeysuckle superior quality of Mixian honeysuckle;Leaf and bud can provide new materials for the comprehensive development of honeysuckle.