Photo‐Enhanced Synergistic Induction of Ferroptosis for Anti‐Cancer Immunotherapy (Adv. Healthcare Mater. 27/2023)

Photodynamic Therapy In article 2300994, Aimin Xu, Weiping Wang, and co-workers develop an NIR light-responsive nanoparticle for photo-enhanced ferroptosis. The nanoparticles undergo charge reversal after irradiation to promote cellular uptake of Ce6 and iFSP1, thereby inducing ferroptosis and immunogenic cell death to promote dendritic cell maturation and T cell activation for tumor inhibition.