α-突触核蛋白
发病机制
肠-脑轴
帕金森病
生物
微生物群
胃肠道
肠道菌群
丁酸盐
血脑屏障
疾病
免疫学
病理
医学
神经科学
中枢神经系统
遗传学
生物化学
发酵
作者
Ying Yang,Tessandra Stewart,Can Zhang,Pan Wang,Zhi Xu,Jinghua Jin,Yang Z. Huang,Zongran Liu,Guoyu Lan,Xingguang Liang,Lifu Sheng,Min Shi,Zhijian Cai,Jing Zhang
摘要
By demonstrating the transportation of α-synuclein through RBC-EVs to the GIT, and its potential association with gut-vascular barrier markers and gut microbiome, this work highlights a potential mechanism by which RBC α-synuclein may impact PD initiation and/or progression. © 2023 The Authors. Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society.
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