Toxicological studies of ethanol leaf extract of Lavandulastoechas on kidney of Wistar rat.

The medicinal ingredients in herbal remedies are derived from plants. Despite the fact that they could offer a wide range of health advantages, they are thought to have a lower likelihood for adverse effects. The medicinal herb lavender (Lavandulastoechas L.) is widely utilized for a variety of medical conditions. The aim of this investigation is to evaluate the toxicological effect of Lavandulastoechas on Wistar rat kidney.Twenty four (24)Animals of either sex were used. Group 1 was given distilled water (10 ml/kg), while groups 2, 3, and 4 were given 50, 100, and 200 mg/kg of Lavandulastoechas, respectively for 28 days. Animals were housed in typical cages and given oral access to the extract for 28 days before being weighed and put to death. A heart puncture was used to get blood, which was then promptly taken for testing.Red blood cell, Hemoglobin, and Mean corpuscular volume levels decreased significantly (P<0.05), but neutrophils, basophiles, eosinophils, and platelets remained constant. At 100 and 200 mg/kg, Lavandulastoechas significantly (P<0.05)loweredK+ levels. Na+ increased significantly (P<0.05)at a dosage of 200 mg/kg. Across doses given, the levels of creatinine, chloride, and urea were not substantially (P<0.05)impacted. A histological analysis shows minimal tubular deformation.The study's findings indicated that the plant might have a negligible impact on the kidney, indicating that it should be used with caution if consumed over an extended period of time.