Advanced glycation end products induce autophagy in endothelial cells through oxidative stress and regulation of the RhoA-mTOR signaling pathway

There was a statistically significant difference in mTOR mRNA expression between Q63LRhoA and T19NRhoA cells. In summary, AGEs induced oxidative damage and autophagy in HUVECs, which may be related to synchronous regulation of the RhoA-mTOR signaling pathway.