Bisphenol S Induced Transgenerational Lipid Accumulation by Triggering Intestine-to-Germline Histone H3K4me3 Modification in Caenorhabditis elegans

/H3K4me3, rather than intestinal, was identified as being responsible for transgenerational inheritance. Our study provides the first evidence elucidating the mechanisms through which environmentally relevant BPS exposure induces lipid accumulation and transmits this effect across generations.