Poorly soluble drugsSeven years ago, in 2013 we published one of the (by far) most downloaded and most cited special issues in the history of the International Journal of Pharmaceutics, which was dedicated to the formulation of poorly water-soluble drugs.This clearly indicates the outstanding importance of this topic in our field.Even today the articles of this 2013 special issue are still very frequently downloaded and referred to: For example, 3 of these papers are among the "top 4 most cited articles" of the journal, when considering the time period "2013today".And also in the last 7 years, numerous research and review articles have been dedicated to the challenges raised by drugs and drug candidates exhibiting poor solubility in water.This is why we, again, devote a special issue of this journal to this "continuously hot topic".