Research status of parenteral nutrition associated cholestasis

Parenteral nutrition associated cholestasis (PNAC) leaded by parenteral nutrition (PN) is one of the most common complications in preterm infants. The etiologies of PNAC are complex, including preterm, low birth weight, long duration of fast, PN, infection and so on. As to PNAC, there is no special treatment currently, but it is very important to prevent PNAC by early enteral nutrition (EN), regulating formula of PN solution, using new lipid emulsion and supplement of probiotics. Key words: Parenteral nutrition; Cholestasis; Infant, premature