PI3K/Akt/mTOR signal transduction pathway and tumor

In recent years, signal transduction pathway and tumor has become an investigative hotspot. In both physiological and pathological conditions, PI3K/Akt/mTOR signal transduction pathway is important in inhibiting apoptosis and promoting proliferation. This pathway also plays an important role in tumor treatment. Thus, the research on the main components of this pathway and the inhibitors of PI3K, Akt, and mTOR has important significance. Key words: PI3K/Akt/mTOR; Signal transduction pathway; Tumor