材料科学
细胞色素c氧化酶
纳米颗粒
癌症治疗
纳米技术
激进的
癌症
酶
组合化学
化学工程
有机化学
化学
医学
内科学
工程类
作者
Zebin Yang,Yu Luo,Yanan Hu,Kaicheng Liang,Gao He,Qian Chen,Qigang Wang,Hangrong Chen
标识
DOI:10.1002/adfm.202170049
摘要
In article number 2007991, Yu Luo, Hangrong Chen, and co-workers report a novel kind of polyvinyl pyrrolidone modified multifunctional iron sulfide nanoparticles (Fe1−xS-PVP NPs), which can in situ generate highly toxic hydroxyl radicals under a tumor environment and simultaneously produce H2S gas to suppress the activity of the enzyme cytochrome c oxidase in cancer cells. The external stimulation of 808 nm near-infrared irradiation will further facilitate this process.
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