心力衰竭
医学
内科学
心脏病学
急性冠脉综合征
冠心病
重症监护医学
心肌梗塞
作者
Vasiliki Tsigkou,Gerasimos Siasos,Evanthia Bletsa,Maria Evi Panoilia,Angeliki Papastavrou,Georgios Kokosias,Evangelos Oikonomou,Nikolaos S. Papageorgiou,Marina Zaromitidou,Γεώργιος Μαρίνος,Manolis Vavuranakis,Christodoulos Stefanadis,Athanasios G. Papavassiliou,Dimitris Tousoulis
标识
DOI:10.2174/0929867326666191016121630
摘要
Intensive research has shed light on the utilization of novel biomarkers which facilitate the diagnosis and prognosis of patients with different medical problems. One of the most important biomarkers especially in the spectrum of heart failure is soluble ST2 (sST2: soluble Suppression of Tumorigenicity 2), which is involved in inflammation, fibrosis and cardiac stress. In the revised 2017 ACC/AHA/HFSA, "Focused Update Guidelines for the Management of Heart Failure" ST2 was given a class-IIa recommendation for the optimal risk assessment in patients with heart failure. Many studies indicate that not only baseline but also serial measurements of ST2 can accurately predict future cardiovascular events in patients with Acute Coronary Syndromes and heart failure. Therefore, in this review, we are going to discuss the studies about the prognostic significance of ST2 in patients with Acute Coronary Syndromes, acute and chronic heart failure.
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