Indium(iii)-catalyzed tandem synthesis of 2-alkynyl-3,3-dichloropyrrolidines and their conversion to 3-chloropyrroles

A convenient route to 2-alkynyl-3,3-dichloropyrrolidines was described by addition of terminal acetylenes to 2,2,4-trichloroaldimines using In(OTf)₃ as a catalyst. In the presence of a base these pyrrolidines were transformed into 3-chloropyrroles.