噬菌体展示
抗体
突变体
生物
人类白细胞抗原
背景(考古学)
等位基因
抗原
癌症研究
基因
分子生物学
突变
遗传学
古生物学
作者
Jacqueline Douglass,Emily Han-Chung Hsiue,Brian J. Mog,Michael S. Hwang,Sarah R. DiNapoli,Alexander H. Pearlman,Michelle S. Miller,Katharine M. Wright,P. Aitana Azurmendi,Qing Wang,Suman Paul,A. Schaefer,Andrew D. Skora,Marco Dal Molin,Maximilian F. Konig,Qiang Liu,Evangeline Watson,Yana Li,Michael Murphy,Drew M. Pardoll
出处
期刊:Science immunology
[American Association for the Advancement of Science]
日期:2021-03-01
卷期号:6 (57)
被引量:168
标识
DOI:10.1126/sciimmunol.abd5515
摘要
genes provided strong genetic evidence for the specificity of the scDbs. Thus, this approach could be applied to other common oncogenic mutations that are difficult to target by conventional means, allowing for more specific anticancer therapeutics.
科研通智能强力驱动
Strongly Powered by AbleSci AI