Domino Reactions for the Syntheses of Chiral Chromanes ‒ Enantioselective Total Syntheses of (‒)-Diversonol, (‒)-Blennolide C, (‒)-Gonytolide C and Formal Synthesis of Siccanin

The general objective of this thesis is to demonstrate the synthetic utility of the domino concept in the complex setting of natural product synthesis. Key step is a palladium-catalyzed domino Wacker/carbonylation/methoxylation reaction that was successfully applied in the enantioselective total syntheses of (‒)-diversonol, (‒)-blennolide C and (‒)-gonytolide C as well as in the formal synthesis of siccanin.