化学
多路复用
石墨氮化碳
吸光度
分子识别
纳米技术
构造(python库)
生物系统
模式识别(心理学)
人工智能
催化作用
计算机科学
色谱法
生物化学
分子
生物信息学
有机化学
生物
光催化
材料科学
程序设计语言
作者
H. Qiu,Fang Pu,Xiang Ran,Chaoqun Liu,Jinsong Ren,Xiaogang Qu
出处
期刊:Analytical Chemistry
[American Chemical Society]
日期:2018-09-28
卷期号:90 (20): 11775-11779
被引量:87
标识
DOI:10.1021/acs.analchem.8b03807
摘要
Nanozymes have been widely used for the construction of colorimetric sensors. However, the simultaneous discrimination of multiple targets using nanozymes is still a challenge. In this work, we construct a multiple-readout system for pattern recognition of proteins using nanozyme. Graphitic carbon nitride (g-C3N4) nanosheets, which possess peroxidase-like activity, are chosen as the single sensing receptor. The catalytic activity of g-C3N4 can be changed to different degrees owing to the different interactions between g-C3N4 and proteins. By choosing different combinations of absorbance intensities at various time points, multichannel information can be extracted from a single material for pattern recognition. The platform avoids the synthesis of multiplex sensing receptors and the requirement of sophisticated instruments, leading to lower cost and time consumption. The study provides a new method for the construction of feasible, convenient, and flexibly nanozyme-based sensing arrays.
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