葛根素
医学
糖尿病
链脲佐菌素
胰岛素抵抗
2型糖尿病
2型糖尿病
有氧运动
抗氧化剂
内科学
内分泌学
药理学
化学
替代医学
生物化学
病理
作者
Qinyuan Yu,Han Wen-zhong,Yixi Zhu,Hua Zhai
出处
期刊:PubMed
[National Institutes of Health]
日期:2017-09-01
卷期号:30 (5(Special)): 1899-1903
被引量:3
摘要
In recent years, the antioxidant efficacy of puerarin has been recognized. However, there is less research on Puerarin used in diabetes. This paper analyzes the effect of puerarin on type II diabetes mellitus induced by streptozotocin combined with orthopaedic footwear. In this study, 80 Sprague Dawley (SD) rats were fed with high fat and high sucrose diet for one month, and 1% streptozotocin (STZ) was used to induce type II diabetes mellitus. After 6 weeks aerobic exercise and puerarin intervention in rats, the effect of aerobic exercise and puerarin intervention on antioxidant ability in diabetic rats was investigated. The results showed that aerobic exercise and puerarin intervention can improve the insulin resistance in rats. Meanwhile, the annual incidence of foot ulcers in diabetic patients is 2%, while orthopaedic footwear can reduce the probability of diabetic foot ulcers. In general, exercise and puerarin intervention can really play a role in the prevention and treatment of diabetes, such as improving the metabolic status of diabetic patients and reducing their dependence on drugs.
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