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Emerging Promise of Phytochemicals in Ameliorating Neurological Disorders.

医学 背景(考古学) 临床试验 疾病 神经保护 好奇心 传统医学 重症监护医学 药理学 神经科学 心理学 生物 内科学 古生物学
作者
Megala Jayaraman,Parijat Dutta,Sabari Krishnan,Khyati Arora,Diveyaa Sivakumar,Hanumanth Rao Balaji Raghavendran
出处
期刊:Cns & Neurological Disorders-drug Targets [Bentham Science Publishers]
卷期号:21
标识
DOI:10.2174/1871527321666220701153926
摘要

The field of medicine and synthetic drug development have advanced rapidly over the past few decades. However, research on alternative medicine such as phytochemicals cannot be ignored. The main reason for prominent curiosity about phytochemicals stems from the belief that usage of natural compounds is safer and has lesser detrimental side effects.The aim of the present review was to discuss in detail with several phytochemicals that have been studied or are being studied in the context of various neurological disorders including depression, Alzheimer's disease, Huntington's disease and even neuroinflammatory disorders such as encephalitis.The potential role of phytochemicals in the treatment or management of symptoms associated with neurological disorders have been included in this article. All data included in this paper has been pooled from various databases including Google Scholar, PubMed, Science Direct, Springer and Wiley Online Library.Phytochemicals have been widely studied for their therapeutic properties associated with neurological disorders. Using various experimental techniques for both in vivo and in vitro experiments, studies have shown that phytochemicals do have antioxidant, anti-inflammatory and neuroprotective activities which play major roles in the treatment of neurological diseases.Even though there has been compelling evidence of the therapeutic role of phytochemicals, further research is still required to evaluate the safety and efficacy of these medicines. Using previously published papers as foundation for additional research such as preclinical studies and clinical trials, phytochemicals can become a safer alternative to synthetic drugs for treating a spectrum of neurological diseases.

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