ipso-Nitration of Arylboronic Acids with Copper Nitrate and Trifluoroacetic Acid

An efficient and novel nitrating reagent has been developed for ipso-nitration of arylboronic acids. By using inexpensive and commercially available Cu(NO3)2/CF3COOH as nitrating reagent, various nitroarenes are produced in moderate to excellent yields (51-96%). Advantages of this procedure are the operational simplicity and no need of extra catalyst. Keywords: Arylboronic acids, Cu(NO3)2/CF3COOH as nitrating reagent, ipso-Nitration, nitroarenes, catalyst-free.