纤维发生
纤维
细胞外基质
胶原纤维
化学
生物物理学
糖胺聚糖
细胞外
结缔组织
基质(化学分析)
细胞生物学
生物化学
生物
遗传学
色谱法
作者
Abu Sayeed Chowdhury,Julia Thom Oxford
标识
DOI:10.1109/csci58124.2022.00108
摘要
Collagen αt (XI) is a minor fibrillar collagen involved in the critical regulation of collagen fibrils such as nucleation, assembly, and regulation of fibril diameter. The amino propeptide domain of the collagen αt (XI) is retained on the surface of the collagen fibril for an extended period of time and may playa crucial role in the interaction with extracellular matrix glycosaminoglycans and other proteins during the process of fibrillogenesis. Understanding the mechanism of action of this protein will ultimately help us understand the organization and assembly of the extracellular matrix that underlies the structural integrity of connective tissues.
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