Catalytic Atroposelective Electrophilic Amination to Access Axially Chiral Diaryl Phenols

An enantioselective synthesis of axially chiral diaryl phenols containing sulfonamide groups has been achieved involving an electrophilic amination of 1,1’‐biaryl‐2,6‐diols with N‐sulfonyl quinone diimines, catalyzed by a chiral phosphoric acid. This atroposelective reaction offers a modular approach to enantiopure diaryl phenols, with good to excellent yields.