Electrochemistry‐Driven Seleno‐Functionalization of Diverse Organic Scaffolds: A Recent Update

Organoselenium compounds have captivated researchers owing to their multifaceted roles in biological systems, medicinal chemistry, materials science, and advanced organic synthesis. This growing interest has spurred the development of practical and sustainable methodologies for constructing carbon-selenium (C─Se) bonds, transforming simple building blocks into architecturally complex molecules. Among these, electro-organic synthesis has emerged as a powerful, green technology for forging such bonds with high efficiency. Electrochemical seleno-functionalization offers a cost-effective and environmentally benign route to valuable selenylated products. This review captures the latest advancements in the field, examining reaction scope, mechanistic pathways, and current challenges. This review summarizes recent progress and highlights emerging perspectives in the electrochemical seleno-functionalization of organic molecules, focusing on studies published during 2018 to mid-2025.