Spinal and Leptomeningeal Infantile Glioma With Raf1 Fusion: Diagnostic Challenges for a Potentially Novel Tumour Type

We report an infantile spinal tumour with diffuse leptomeningeal dissemination and features of a glioma with CUX1::RAF1 fusion and the DNA-methylation class, infant-type hemispheric glioma. This strange case was similar to a previously reported tumour reported in the literature, which clustered perfectly with our case. Further reports are needed to confirm the hypothesis that this neoplasm represents a novel tumour type.