过氧化氢
发酵乳杆菌
氧化应激
活性氧
微生物学
化学
超氧化物
抗菌剂
抗氧化剂
脂质过氧化
拉伤
激进的
超氧化物歧化酶
乳酸菌
过氧化氢酶
生物化学
沙门氏菌
细菌
谷胱甘肽
生物
乳酸
酶
植物乳杆菌
发酵
解剖
遗传学
作者
Tiiu Kullisaar,Mihkel Zilmer,Marika Mikelsaar,Tiiu Vihalemm,Heidi Annuk,Česlava Kairane,Ann Kilk
标识
DOI:10.1016/s0168-1605(01)00674-2
摘要
Two antioxidative strains tentatively identified as Lactobacillus fermentum, E-3 and E-18, were isolated from intestinal microflora of a healthy child. Survival time of these strains in the presence of reactive oxygen species (ROS), like hydrogen peroxide, superoxide anions and hydroxyl radicals, was significantly increased compared with a non-antioxidative strain, and also was quite similar to a highly ROS resistant strain of Salmonella typhimurium. E-3 and E-8 contain a remarkable level of glutathione, express Mn-SOD, which is important for the prevention of lipid peroxidation, and secrete hydrogen peroxide. Their significant antimicrobial activity combined with antioxidative properties may serve as defensive principles in the intestinal microbial ecosystem and overcome exo- and endogenous oxidative stress.
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