自噬                        
                
                                
                        
                            医学                        
                
                                
                        
                            细胞内                        
                
                                
                        
                            细胞器                        
                
                                
                        
                            免疫系统                        
                
                                
                        
                            细胞生物学                        
                
                                
                        
                            免疫学                        
                
                                
                        
                            生物                        
                
                                
                        
                            生物化学                        
                
                                
                        
                            细胞凋亡                        
                
                        
                    
            作者
            
                Noboru Mizushima,Beth Levine            
         
                    
        
    
            
            标识
            
                                    DOI:10.1056/nejmra2022774
                                    
                                
                                 
         
        
                
            摘要
            
            Autophagy is a complex process of intracellular degradation of senescent or malfunctioning organelles. Dysregulated autophagy is associated with certain cancers, neurodegenerative diseases, immune dysfunction, and aging. Therapies aimed at regulating autophagy are being developed.
         
            
 
                 
                
                    
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