化学
恶唑
鞘脂
甲酰胺
神经酰胺
生物活性
药理学
铅化合物
生物化学
立体化学
体外
生物
细胞凋亡
作者
Samantha Caputo,Simona Di Martino,Vincenzo Cilibrasi,Piero Tardia,Marco Mazzonna,Debora Russo,Ilaria Penna,Maria Summa,Sine Mandrup Bertozzi,Natalia Realini,Natasha Margaroli,Marco Migliore,Giuliana Ottonello,Min Liu,Peter T. Lansbury,Andrea Armirotti,Rosalia Bertorelli,Soumya S. Ray,Renato T. Skerlj,Rita Scarpelli
标识
DOI:10.1021/acs.jmedchem.0c01561
摘要
enriches the arsenal of promising lead compounds that may therefore act as useful pharmacological tools for investigating the potential therapeutic effects of AC inhibition in relevant sphingolipid-mediated disorders.
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