Lactobacillus GG: Bacteriology and Clinical Applications

Lactobacillus rhamnous GG (LGG) has been studied extensively in humans and experimental animals for a wide variety of uses. At present, there is strong evidence that LGG can be used in acute diarrhea and antibiotic-associated diarrhea. Data suggest that LGG may be useful for treatment and prevention of atopic disease and for prevention of infections acquired in daycare, traveler's diarrhea, and dental caries. Results from studies in inflammatory bowel disease, Clostridium difficile, and cystic fibrosis are promising. Studies of LGG for cancer prevention; rheumatoid arthritis, irritable bowel syndrome, liver disease, and diabetes warrant more research.