Effect of Mussaenoside on Lipopolysaccharide-induced Nitric Oxide Releasing in RAW 264.7 Cells

Objective: To study the effect of Mussaenoside on lipopolysaccharide-induced nitric oxide releasing in RAW 264.7 cells. Methods: The cell pattern with RAW264.7 cells activated by lipopolysaccharides(LPS) was established, and the production of NO was examined by NO detection kit. Results: Mussaenoside can obviously reduce the production and release of NO in RAW 264.7 cells, induced by LPS, with statistical difference(P 0.01), comparing with control group. Conclusion: Mussaenoside maybe present an anti-inflammatory effect by reducing NO production.