Environmental toxicants can not only induce the toxicity through acute or chronic exposure,but also induce the toxicity which can be further transferred from exposed parents to their progeny.In this review,the research progresses on the transfer of toxicity induced by different metals and organic pollutants,such as sulfamethoxazole and acrylamide,from exposed parents to their progeny,the transfer characteristics of toxicity from exposed parents to their progeny,and the possible regulation mechanisms on toxicity transfer from exposed parents to their progeny in nematode Caenorhabditis elegans were reviewed.