Preliminary study of cognition assessment by Montreal Cognitive Assessment Scale in the patients with vascular mild cognitive impairment

Objective To investigate the feasibility of application of Montreal Cognitive Assessment Scale(MoCA) chinese version to the assessment of global cognition in the patients with vascular mild cognitive impairment(vMCI).Methods Fifty vMCI patients and fifty healthy normal subjects were included in the study.Their cognitive functions were assessed with MoCA and Mini-Mental State Examination(MMSE),and the results were analyzed and compared.Results There was a significant correlation between the MMSE and the MoCA scores in both groups(P0.05),and MoCA scores were significantly lower than MMSE scores(P0.05).The significant differences presented between vMCI group and control group in the comparison of sub-item score and total score in MoCA.The MoCA had the sensitivity of 84.0% and the specificity of 76.0% for detecting vMCI,the sensitivity and the specificity of MMSE was 46.0% and 98%,respectively.Conclusion The MoCA has higher sensitivity than the MMSE for cognitive assessment in the patients with vMCI.