Objective To determine the safe method of perioperative glycemic control in the traumatic patients with diabetes mellitus. Methods 50 cases of diabetic patients underwent various traumatic procedures were retrospectively analyzed. Results The associated diabetes occurred frequently in type 2、elderly patients. 5 cases were missed diagnosis owing to the insidious diabetic courses,and 1 case died of severe. wound of brain. Conclusion Intravenous regular insulin administration during perioperative period is an effective and safe method for management of the diabetic patients.