状态5
血管生成
车站3
斯达
免疫系统
癌症
免疫学
生物
癌症研究
信号转导
细胞生物学
遗传学
出处
期刊:Nature Reviews Cancer
[Springer Nature]
日期:2004-02-01
卷期号:4 (2): 97-105
被引量:2069
摘要
Tumour cells acquire the ability to proliferate uncontrollably, resist apoptosis, sustain angiogenesis and evade immune surveillance. STAT proteins — especially STAT3 and STAT5 — regulate all of these processes and are persistently activated in a surprisingly large number of human cancers. Consequently, STAT proteins are emerging — unexpectedly — as ideal targets for cancer therapy.
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