[Objective]To observe salvia miltiorrhiza astragalus membranaceus injection treatment of coronary heart disease angina pectoris curative effect.[Methods]Using random parallel control method,150cases of hospitalized patients in hospital order method were randomly divided into three groups. I group of 50cases of 20 ml 250 ml of astragalus membranaceus injection+5% glucose solution or 0.9% saline 250ml,1/d. II group of 50 cases of 20 ml 250 ml of salvia miltiorrhiza injection+5% glucose solution or 0.9% saline 250ml,1/d.III group of 50 cases of 20 ml 250 ml of salvia miltiorrhiza injection+5% glucose solution or 0.9% saline 250ml,1/d;20 ml 250 ml of astragalus membranaceus injection + 5% glucose solution or 0.9% saline 250 ml,1/d.Continuous treatment of 10d to 1 course of treatment. Observation of clinical symptoms,angina pectoris,adverse reactions. Continuous treatment 1 treatment course,judge curative effect.[Results]III group 46 cases were markedly improved,effective in 2 cases,4 cases were invalid,the total effective rate was 96.00%. II group of18 cases were markedly effective,effective 22 cases,10 cases were invalid,the total effective rate was 80.00%.I group of 18 cases were markedly effective,effective 20 cases,12 cases ineffective,the total effective rate was76.00%. Three groups of efficacy differences statistically significant(P0.05). Three groups of angina pectoris index were improved(P0.05),group is better than that of II,I(P0.05). Salvia miltiorrhiza astragalus membranaceus injection.[Conclusion]The effect of the treatment of coronary heart disease angina pectoris,significantly better than the single drug,used to be promoted.